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Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation

Mycosis fungoides (MF) is the most common variant of primary cutaneous T-cell lymphoma (CTCL). It is generally associated with an indolent clinical course and characterised by well-defined clinicopathological features. Although rare, CTCLs constitute 65% of all cutaneous lymphoid malignancies, of wh...

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Autores principales: Chaudhary, Savita, Bansal, Cherry, Ranga, Upasna, Singh, KK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738031/
https://www.ncbi.nlm.nih.gov/pubmed/23940492
http://dx.doi.org/10.3332/ecancer.2013.337
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author Chaudhary, Savita
Bansal, Cherry
Ranga, Upasna
Singh, KK
author_facet Chaudhary, Savita
Bansal, Cherry
Ranga, Upasna
Singh, KK
author_sort Chaudhary, Savita
collection PubMed
description Mycosis fungoides (MF) is the most common variant of primary cutaneous T-cell lymphoma (CTCL). It is generally associated with an indolent clinical course and characterised by well-defined clinicopathological features. Although rare, CTCLs constitute 65% of all cutaneous lymphoid malignancies, of which 50% are patients with MF. The erythrodermic variants of MF, a malignancy of mature, skin homing and clonal T lymphocytes, usually present in mid to late adulthood. Association with hypereosinophilia is important in prognosis. We report a case of erythrodermic MF with hypereosinophilic syndrome in a 22-year-old female presenting with gradually progressive intractable erythroderma with intensely pruritic multiple papules, plaques, and nodules involving more than 90% of body surface area. Diagnosis was confirmed by histopathological examination and immunophenotyping from multiple skin biopsies.
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spelling pubmed-37380312013-08-12 Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation Chaudhary, Savita Bansal, Cherry Ranga, Upasna Singh, KK Ecancermedicalscience Case Report Mycosis fungoides (MF) is the most common variant of primary cutaneous T-cell lymphoma (CTCL). It is generally associated with an indolent clinical course and characterised by well-defined clinicopathological features. Although rare, CTCLs constitute 65% of all cutaneous lymphoid malignancies, of which 50% are patients with MF. The erythrodermic variants of MF, a malignancy of mature, skin homing and clonal T lymphocytes, usually present in mid to late adulthood. Association with hypereosinophilia is important in prognosis. We report a case of erythrodermic MF with hypereosinophilic syndrome in a 22-year-old female presenting with gradually progressive intractable erythroderma with intensely pruritic multiple papules, plaques, and nodules involving more than 90% of body surface area. Diagnosis was confirmed by histopathological examination and immunophenotyping from multiple skin biopsies. Cancer Intelligence 2013-08-05 /pmc/articles/PMC3738031/ /pubmed/23940492 http://dx.doi.org/10.3332/ecancer.2013.337 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chaudhary, Savita
Bansal, Cherry
Ranga, Upasna
Singh, KK
Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title_full Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title_fullStr Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title_full_unstemmed Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title_short Erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
title_sort erythrodermic mycosis fungoides with hypereosinophilic syndrome: a rare presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738031/
https://www.ncbi.nlm.nih.gov/pubmed/23940492
http://dx.doi.org/10.3332/ecancer.2013.337
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