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Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer

INTRODUCTION: Quiescin sulfhydryl oxidase 1 (QSOX1) oxidizes sulfhydryl groups to form disulfide bonds in proteins. Tumor specific expression of QSOX1 has been reported for numerous tumor types. In this study, we investigate QSOX1 as a marker of breast tumor progression and evaluate the role of QSOX...

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Detalles Bibliográficos
Autores principales: Katchman, Benjamin A, Ocal, I Tolgay, Cunliffe, Heather E, Chang, Yu-Hui, Hostetter, Galen, Watanabe, Aprill, LoBello, Janine, Lake, Douglas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738157/
https://www.ncbi.nlm.nih.gov/pubmed/23536962
http://dx.doi.org/10.1186/bcr3407