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Assessment of leukocyte trafficking in humans using the cantharidin blister model
The cantharidin blister model provides an in vivo assessment of the innate inflammatory response in humans. It allows researchers to profile the acute and resolving inflammatory response in healthy and diseased states and for the design of crossover trials for the testing of new treatments for acute...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738319/ https://www.ncbi.nlm.nih.gov/pubmed/24175059 http://dx.doi.org/10.1258/cvd.2012.012009 |
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author | Jenner, William J Gilroy, Derek W |
author_facet | Jenner, William J Gilroy, Derek W |
author_sort | Jenner, William J |
collection | PubMed |
description | The cantharidin blister model provides an in vivo assessment of the innate inflammatory response in humans. It allows researchers to profile the acute and resolving inflammatory response in healthy and diseased states and for the design of crossover trials for the testing of new treatments for acute inflammation. Below we describe the materials and methods required to prepare, induce, aspirate and analyse the forearm cantharidin blisters, in preparation for future study design. |
format | Online Article Text |
id | pubmed-3738319 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-37383192013-10-30 Assessment of leukocyte trafficking in humans using the cantharidin blister model Jenner, William J Gilroy, Derek W JRSM Cardiovasc Dis Protocols The cantharidin blister model provides an in vivo assessment of the innate inflammatory response in humans. It allows researchers to profile the acute and resolving inflammatory response in healthy and diseased states and for the design of crossover trials for the testing of new treatments for acute inflammation. Below we describe the materials and methods required to prepare, induce, aspirate and analyse the forearm cantharidin blisters, in preparation for future study design. SAGE Publications 2012-04-05 /pmc/articles/PMC3738319/ /pubmed/24175059 http://dx.doi.org/10.1258/cvd.2012.012009 Text en © 2012 Royal Society of Medicine Press http://creativecommons.org/licenses/by-nc/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/2.0/), which permits non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Protocols Jenner, William J Gilroy, Derek W Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title | Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title_full | Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title_fullStr | Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title_full_unstemmed | Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title_short | Assessment of leukocyte trafficking in humans using the cantharidin blister model |
title_sort | assessment of leukocyte trafficking in humans using the cantharidin blister model |
topic | Protocols |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738319/ https://www.ncbi.nlm.nih.gov/pubmed/24175059 http://dx.doi.org/10.1258/cvd.2012.012009 |
work_keys_str_mv | AT jennerwilliamj assessmentofleukocytetraffickinginhumansusingthecantharidinblistermodel AT gilroyderekw assessmentofleukocytetraffickinginhumansusingthecantharidinblistermodel |