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Identification and Functional Analysis of Trypanosoma cruzi Genes That Encode Proteins of the Glycosylphosphatidylinositol Biosynthetic Pathway

BACKGROUND: Trypanosoma cruzi is a protist parasite that causes Chagas disease. Several proteins that are essential for parasite virulence and involved in host immune responses are anchored to the membrane through glycosylphosphatidylinositol (GPI) molecules. In addition, T. cruzi GPI anchors have i...

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Detalles Bibliográficos
Autores principales: Cardoso, Mariana S., Junqueira, Caroline, Trigueiro, Ricardo C., Shams-Eldin, Hosam, Macedo, Cristiana S., Araújo, Patrícia R., Gomes, Dawidson A., Martinelli, Patrícia M., Kimmel, Jürgen, Stahl, Philipp, Niehus, Sebastian, Schwarz, Ralph T., Previato, José O., Mendonça-Previato, Lucia, Gazzinelli, Ricardo T., Teixeira, Santuza M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738449/
https://www.ncbi.nlm.nih.gov/pubmed/23951384
http://dx.doi.org/10.1371/journal.pntd.0002369