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Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans

Proliferation and morphogenesis in eukaryotic cells depend on the concerted activity of Rho-type GTPases, including Ras, Cdc42, and Rac. The sexually dimorphic fungus Cryptococcus neoformans, which encodes paralogous, non-essential copies of all three, provides a unique model in which to examine the...

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Detalles Bibliográficos
Autores principales: Ballou, Elizabeth Ripley, Kozubowski, Lukasz, Nichols, Connie B., Alspaugh, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738472/
https://www.ncbi.nlm.nih.gov/pubmed/23950731
http://dx.doi.org/10.1371/journal.pgen.1003687