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Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans
Proliferation and morphogenesis in eukaryotic cells depend on the concerted activity of Rho-type GTPases, including Ras, Cdc42, and Rac. The sexually dimorphic fungus Cryptococcus neoformans, which encodes paralogous, non-essential copies of all three, provides a unique model in which to examine the...
Autores principales: | Ballou, Elizabeth Ripley, Kozubowski, Lukasz, Nichols, Connie B., Alspaugh, J. Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738472/ https://www.ncbi.nlm.nih.gov/pubmed/23950731 http://dx.doi.org/10.1371/journal.pgen.1003687 |
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