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Stabilization of Myc through Heterotypic Poly-Ubiquitination by mLANA Is Critical for γ-Herpesvirus Lymphoproliferation

Host colonization by lymphotropic γ-herpesviruses depends critically on expansion of viral genomes in germinal center (GC) B-cells. Myc is essential for the formation and maintenance of GCs. Yet, the role of Myc in the pathogenesis of γ-herpesviruses is still largely unknown. In this study, Myc was...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Lénia, Popov, Nikita, Kaye, Kenneth M., Simas, J. Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738482/ https://www.ncbi.nlm.nih.gov/pubmed/23950719 http://dx.doi.org/10.1371/journal.ppat.1003554

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