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Brucella Modulates Secretory Trafficking via Multiple Type IV Secretion Effector Proteins

The intracellular pathogenic bacterium Brucella generates a replicative vacuole (rBCV) derived from the endoplasmic reticulum via subversion of the host cell secretory pathway. rBCV biogenesis requires the expression of the Type IV secretion system (T4SS) VirB, which is thought to translocate effect...

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Detalles Bibliográficos
Autores principales: Myeni, Sebenzile, Child, Robert, Ng, Tony W., Kupko, John J., Wehrly, Tara D., Porcella, Stephen F., Knodler, Leigh A., Celli, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738490/
https://www.ncbi.nlm.nih.gov/pubmed/23950720
http://dx.doi.org/10.1371/journal.ppat.1003556