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SIGIRR, a Negative Regulator of TLR/IL-1R Signalling Promotes Microbiota Dependent Resistance to Colonization by Enteric Bacterial Pathogens

Enteric bacterial pathogens such as enterohemorrhagic E. coli (EHEC) and Salmonella Typhimurium target the intestinal epithelial cells (IEC) lining the mammalian gastrointestinal tract. Despite expressing innate Toll-like receptors (TLRs), IEC are innately hypo-responsive to most bacterial products....

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Detalles Bibliográficos
Autores principales:	Sham, Ho Pan, Yu, Emily Yi Shan, Gulen, Muhammet F., Bhinder, Ganive, Stahl, Martin, Chan, Justin M., Brewster, Lara, Morampudi, Vijay, Gibson, Deanna L., Hughes, Michael R., McNagny, Kelly M., Li, Xiaoxia, Vallance, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738496/ https://www.ncbi.nlm.nih.gov/pubmed/23950714 http://dx.doi.org/10.1371/journal.ppat.1003539

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