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The Multifunctional Ca(2+)/Calmodulin-Dependent Kinase IIδ (CaMKIIδ) Regulates Arteriogenesis in a Mouse Model of Flow-Mediated Remodeling
OBJECTIVE: Sustained hemodynamic stress mediated by high blood flow promotes arteriogenesis, the outward remodeling of existing arteries. Here, we examined whether Ca(2+)/calmodulin-dependent kinase II (CaMKII) regulates arteriogenesis. METHODS AND RESULTS: Ligation of the left common carotid led to...
Autores principales: | Scott, Jason A., Klutho, Paula J., El Accaoui, Ramzi, Nguyen, Emily, Venema, Ashlee N., Xie, Litao, Jiang, Shuxia, Dibbern, Megan, Scroggins, Sabrina, Prasad, Anand M., Luczak, Elisabeth D., Davis, Melissa K., Li, Weiwei, Guan, Xiaoqun, Backs, Johannes, Schlueter, Annette J., Weiss, Robert M., Miller, Francis J., Anderson, Mark E., Grumbach, Isabella M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738514/ https://www.ncbi.nlm.nih.gov/pubmed/23951185 http://dx.doi.org/10.1371/journal.pone.0071550 |
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