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HLA-DO as the Optimizer of Epitope Selection for MHC Class II Antigen Presentation
Processing of antigens for presentation to helper T cells by MHC class II involves HLA-DM (DM) and HLA-DO (DO) accessory molecules. A mechanistic understanding of DO in this process has been missing. The leading model on its function proposes that DO inhibits the effects of DM. To directly study DO...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738515/ https://www.ncbi.nlm.nih.gov/pubmed/23951115 http://dx.doi.org/10.1371/journal.pone.0071228 |