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Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation
BACKGROUND: ADF/cofilin proteins are key regulators of actin dynamics. Their function is inhibited by LIMK-mediated phosphorylation at Ser-3. Previous in vitro studies have shown that dependent on its concentration, cofilin either depolymerizes F-actin (at low cofilin concentrations) or promotes act...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738525/ https://www.ncbi.nlm.nih.gov/pubmed/23951242 http://dx.doi.org/10.1371/journal.pone.0071769 |