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No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix Vaccination Campaign in Finland

BACKGROUND: Narcolepsy cataplexy syndrome, characterised by excessive daytime sleepiness and cataplexy, is strongly associated with a genetic marker, human leukocyte antigen (HLA) DQB1*06:02. A sudden increase in the incidence of childhood narcolepsy was observed after vaccination with AS03-adjuvant...

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Detalles Bibliográficos
Autores principales: Melén, Krister, Partinen, Markku, Tynell, Janne, Sillanpää, Maarit, Himanen, Sari-Leena, Saarenpää-Heikkilä, Outi, Hublin, Christer, Olsen, Päivi, Ilonen, Jorma, Nohynek, Hanna, Syrjänen, Ritva, Kilpi, Terhi, Vuorela, Arja, Kirjavainen, Turkka, Vaarala, Outi, Julkunen, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738560/
https://www.ncbi.nlm.nih.gov/pubmed/23950869
http://dx.doi.org/10.1371/journal.pone.0068402