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Antimicrobial activity of amazonian medicinal plants

OBJECTIVES: The aqueous extracts of currently utilized Amazonian medicinal plants were assayed in vitro searching for antimicrobial activity against human and animal pathogenic microorganisms. METHODS: Medium resuspended lyophilized aqueous extracts of different organs of Amazonian medicinal plants...

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Autores principales: Oliveira, Amanda A, Segovia, Jorge FO, Sousa, Vespasiano YK, Mata, Elida CG, Gonçalves, Magda CA, Bezerra, Roberto M, Junior, Paulo OM, Kanzaki, Luís IB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738913/
https://www.ncbi.nlm.nih.gov/pubmed/23961431
http://dx.doi.org/10.1186/2193-1801-2-371
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author Oliveira, Amanda A
Segovia, Jorge FO
Sousa, Vespasiano YK
Mata, Elida CG
Gonçalves, Magda CA
Bezerra, Roberto M
Junior, Paulo OM
Kanzaki, Luís IB
author_facet Oliveira, Amanda A
Segovia, Jorge FO
Sousa, Vespasiano YK
Mata, Elida CG
Gonçalves, Magda CA
Bezerra, Roberto M
Junior, Paulo OM
Kanzaki, Luís IB
author_sort Oliveira, Amanda A
collection PubMed
description OBJECTIVES: The aqueous extracts of currently utilized Amazonian medicinal plants were assayed in vitro searching for antimicrobial activity against human and animal pathogenic microorganisms. METHODS: Medium resuspended lyophilized aqueous extracts of different organs of Amazonian medicinal plants were assayed by in vitro screening for antimicrobial activity. ATCC and standardized microorganisms obtained from Oswaldo Cruz Foundation/Brazil were individually and homogeneously grown in agar plate, and holes previously perforated in the gel were filled with diluted plant aqueous extracts. Inhibition halos were evaluated and controlled by the use of the fluoroquinolone ciprofloxacin. RESULTS: The Amazonian medicinal plants, Hymenelobium petraeum showed inhibitory activity over Staphylococcus aureus, Enterococcus faecalis, Salmonella enterica serovar Typhi, Acinetobacter baumannii and Candida albicans, while Vatairea guianensis and Symphonia globulifera presented inhibitory activity exclusively for Staphylococcus aureus. Also, Ptychopetalum olacoides and Pentaclethra macroloba inhibited the growth of Klebsiella ozaenae and Acinetobacter baumannii. CONCLUSION: The aqueous botanic extracts that showed activity against microroganisms of ATTC and Osvaldo Cruz strains had at least 40% of antimicrobial activity when compared to halo inhibition produced by the commercial antibiotic ciprofloxacin utilized as a control. Of all plants extracts assayed, the Hymenelobium petraeum had the best performance, sometimes exhibiting higher activity than ciprofloxacin. It is not well-defined by the physicians the exact indication of the majority of medicinal plants in the Amazon area in Brazil. Natives utilize the plants according to their symptoms, based on the traditional knowledge transmitted orally from generation to generation, among Amerindians, Afrodescendents and ethnic mixed populations. A significant number of Amazonian medicinal plants are totally unknown related to their medicinal properties including mechanism of action and therapeutic effects, as very few information is reported in the scientific literature. A tiny amount of data is presented, as the preliminary antimicrobial properties of the medicinal plants here accessed, under the urgent necessity of new antibiotics in the market and in face of the increased resistance of infectious microorganisms to antimicrobials.
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spelling pubmed-37389132013-08-13 Antimicrobial activity of amazonian medicinal plants Oliveira, Amanda A Segovia, Jorge FO Sousa, Vespasiano YK Mata, Elida CG Gonçalves, Magda CA Bezerra, Roberto M Junior, Paulo OM Kanzaki, Luís IB Springerplus Research OBJECTIVES: The aqueous extracts of currently utilized Amazonian medicinal plants were assayed in vitro searching for antimicrobial activity against human and animal pathogenic microorganisms. METHODS: Medium resuspended lyophilized aqueous extracts of different organs of Amazonian medicinal plants were assayed by in vitro screening for antimicrobial activity. ATCC and standardized microorganisms obtained from Oswaldo Cruz Foundation/Brazil were individually and homogeneously grown in agar plate, and holes previously perforated in the gel were filled with diluted plant aqueous extracts. Inhibition halos were evaluated and controlled by the use of the fluoroquinolone ciprofloxacin. RESULTS: The Amazonian medicinal plants, Hymenelobium petraeum showed inhibitory activity over Staphylococcus aureus, Enterococcus faecalis, Salmonella enterica serovar Typhi, Acinetobacter baumannii and Candida albicans, while Vatairea guianensis and Symphonia globulifera presented inhibitory activity exclusively for Staphylococcus aureus. Also, Ptychopetalum olacoides and Pentaclethra macroloba inhibited the growth of Klebsiella ozaenae and Acinetobacter baumannii. CONCLUSION: The aqueous botanic extracts that showed activity against microroganisms of ATTC and Osvaldo Cruz strains had at least 40% of antimicrobial activity when compared to halo inhibition produced by the commercial antibiotic ciprofloxacin utilized as a control. Of all plants extracts assayed, the Hymenelobium petraeum had the best performance, sometimes exhibiting higher activity than ciprofloxacin. It is not well-defined by the physicians the exact indication of the majority of medicinal plants in the Amazon area in Brazil. Natives utilize the plants according to their symptoms, based on the traditional knowledge transmitted orally from generation to generation, among Amerindians, Afrodescendents and ethnic mixed populations. A significant number of Amazonian medicinal plants are totally unknown related to their medicinal properties including mechanism of action and therapeutic effects, as very few information is reported in the scientific literature. A tiny amount of data is presented, as the preliminary antimicrobial properties of the medicinal plants here accessed, under the urgent necessity of new antibiotics in the market and in face of the increased resistance of infectious microorganisms to antimicrobials. Springer International Publishing 2013-08-05 /pmc/articles/PMC3738913/ /pubmed/23961431 http://dx.doi.org/10.1186/2193-1801-2-371 Text en © Oliveira et al.; licensee Springer. 2013 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Oliveira, Amanda A
Segovia, Jorge FO
Sousa, Vespasiano YK
Mata, Elida CG
Gonçalves, Magda CA
Bezerra, Roberto M
Junior, Paulo OM
Kanzaki, Luís IB
Antimicrobial activity of amazonian medicinal plants
title Antimicrobial activity of amazonian medicinal plants
title_full Antimicrobial activity of amazonian medicinal plants
title_fullStr Antimicrobial activity of amazonian medicinal plants
title_full_unstemmed Antimicrobial activity of amazonian medicinal plants
title_short Antimicrobial activity of amazonian medicinal plants
title_sort antimicrobial activity of amazonian medicinal plants
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738913/
https://www.ncbi.nlm.nih.gov/pubmed/23961431
http://dx.doi.org/10.1186/2193-1801-2-371
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