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Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16

Fibroblast growth factors (Fgfs) are pleiotropic proteins involved in development, repair and metabolism. Fgf16 is predominantly expressed in the heart. However, as the heart function is essentially normal in Fgf16 knockout mice, its role has remained unclear. To elucidate the pathophysiological rol...

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Detalles Bibliográficos
Autores principales: Matsumoto, Emi, Sasaki, Sayaka, Kinoshita, Hideyuki, Kito, Takuya, Ohta, Hiroya, Konishi, Morichika, Kuwahara, Koichiro, Nakao, Kazuwa, Itoh, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738920/
https://www.ncbi.nlm.nih.gov/pubmed/23600527
http://dx.doi.org/10.1111/gtc.12055