X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk

X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here, we demonstrate a novel function of XIAP as a regulator of neurite outgrowth in neuronal cells. In PC12 cells, XIAP overexpression prevents NGF-induced neuronal differentiation, whereas NGF...

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Detalles Bibliográficos
Autores principales: Fadó, Rut, Moubarak, Rana S., Miñano-Molina, Alfredo J., Barneda-Zahonero, Bruna, Valero, Jorge, Saura, Carlos A., Moran, Julio, Comella, Joan X., Rodríguez-Álvarez, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739015/
https://www.ncbi.nlm.nih.gov/pubmed/23928917
http://dx.doi.org/10.1038/srep02397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739015/
https://www.ncbi.nlm.nih.gov/pubmed/23928917
http://dx.doi.org/10.1038/srep02397

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