Cargando…

L-type Ca(V)1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for Ca(V)1.2-mediated control of cochlear BDNF expression

Voltage-gated L-type Ca(2+) channels (L-VGCCs) like Ca(V)1.2 are assumed to play a crucial role for controlling release of trophic peptides including brain-derived neurotrophic factor (BDNF). In the inner ear of the adult mouse, besides the well-described L-VGCC Ca(V)1.3, Ca(V)1.2 is also expressed....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuccotti, Annalisa, Lee, Sze C., Campanelli, Dario, Singer, Wibke, Satheesh, Somisetty V., Patriarchi, Tommaso, Geisler, Hyun-Soon, Köpschall, Iris, Rohbock, Karin, Nothwang, Hans G., Hu, Jing, Hell, Johannes W., Schimmang, Thomas, Rüttiger, Lukas, Knipper, Marlies
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739414/ https://www.ncbi.nlm.nih.gov/pubmed/23950737 http://dx.doi.org/10.3389/fnmol.2013.00020

Ejemplares similares

Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea
por: Marchetta, Philine, et al.
Publicado: (2022)

Fine Tuning of Ca(V)1.3 Ca(2+) Channel Properties in Adult Inner Hair Cells Positioned in the Most Sensitive Region of the Gerbil Cochlea
por: Zampini, Valeria, et al.
Publicado: (2014)

The Reduced Cochlear Output and the Failure to Adapt the Central Auditory Response Causes Tinnitus in Noise Exposed Rats
por: Rüttiger, Lukas, et al.
Publicado: (2013)

Dynamic L-type Ca(V)1.2 channel trafficking facilitates Ca(V)1.2 clustering and cooperative gating
por: Ghosh, Debapriya, et al.
Publicado: (2018)

Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway
por: Peixoto Pinheiro, Barbara, et al.
Publicado: (2020)

Visualizing BDNF Transcript Usage During Sound-Induced Memory Linked Plasticity
por: Matt, Lucas, et al.
Publicado: (2018)

Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF
por: Marchetta, Philine, et al.
Publicado: (2020)

BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury
por: Chumak, Tetyana, et al.
Publicado: (2015)

Effect of Ca(v)β Subunits on Structural Organization of Ca(v)1.2 Calcium Channels
por: Kobrinsky, Evgeny, et al.
Publicado: (2009)

A pink mouse reports the switch from red to green fluorescence upon Cre-mediated recombination
por: Hartwich, Heiner, et al.
Publicado: (2012)

Orchestrating Ca(2+) influx through Ca(V)1.2 and Ca(V)3.x channels in human cerebral arteries
por: Collier, Daniel M., et al.
Publicado: (2015)

Ca(V)β-subunit dependence of forward and reverse trafficking of Ca(V)1.2 calcium channels
por: Ferron, Laurent, et al.
Publicado: (2022)

BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo
por: Singer, Wibke, et al.
Publicado: (2018)

AKAP5 complex facilitates purinergic modulation of vascular L-type Ca(2+) channel Ca(V)1.2
por: Prada, Maria Paz, et al.
Publicado: (2020)

Mechanisms and Regulation of Cardiac Ca(V)1.2 Trafficking
por: Westhoff, Maartje, et al.
Publicado: (2021)

Specific synaptopathies diversify brain responses and hearing disorders: you lose the gain from early life
por: Knipper, Marlies, et al.
Publicado: (2015)

Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca(2+) channel Ca(V)1.2
por: Voelker, Taylor L., et al.
Publicado: (2023)

Expression and Localization of CaBP Ca(2+) Binding Proteins in the Mouse Cochlea
por: Yang, Tian, et al.
Publicado: (2016)

Spatiotemporal Control of Vascular Ca(V)1.2 by α1(C) S1928 Phosphorylation
por: Martín-Aragón Baudel, Miguel, et al.
Publicado: (2022)

Elementary properties of Ca(V)1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells
por: Zampini, Valeria, et al.
Publicado: (2010)

Graded Ca(2+)/calmodulin-dependent coupling of voltage-gated Ca(V)1.2 channels
por: Dixon, Rose E, et al.
Publicado: (2015)

Increased Ca(2+) influx through Ca(V)1.2 drives aortic valve calcification
por: Matsui, Maiko, et al.
Publicado: (2022)

Ca(V)1.2/Ca(V)3.x channels mediate divergent vasomotor responses in human cerebral arteries
por: Harraz, Osama F., et al.
Publicado: (2015)

Ca(v)1.2, Cell Proliferation, and New Target in Atherosclerosis
por: Soldatov, Nikolai M.
Publicado: (2013)

Molecular Determinants of Ca(v)1.2 Calcium Channel Inactivation
por: Soldatov, Nikolai M.
Publicado: (2012)

Intercellular Ca(2+) signalling in the adult mouse cochlea
por: Sirko, Piotr, et al.
Publicado: (2018)

Interaction of diltiazem with an intracellularly accessible binding site on Ca(V)1.2
por: Shabbir, W, et al.
Publicado: (2011)

Methods for quantification of pore–voltage sensor interaction in Ca(V)1.2
por: Beyl, S., et al.
Publicado: (2013)

Mechanism of adrenergic Ca(V)1.2 stimulation revealed by proximity proteomics
por: Liu, Guoxia, et al.
Publicado: (2020)

Ca(V)1.2 channelopathic mutations evoke diverse pathophysiological mechanisms
por: Bamgboye, Moradeke A., et al.
Publicado: (2022)

Burst activity and ultrafast activation kinetics of Ca(V)1.3 Ca(2+) channels support presynaptic activity in adult gerbil hair cell ribbon synapses
por: Zampini, Valeria, et al.
Publicado: (2013)

Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of Ca(V)1.2 calcium channels in hippocampal neurons
por: Folci, Alessandra, et al.
Publicado: (2018)

Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca(V)1.2
por: Bartels, Peter, et al.
Publicado: (2022)

Characterization of Ca(V)1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and Ca(V)1.2 exon 33 expressions in human heart failure
por: Wang, Juejin, et al.
Publicado: (2017)

Deletion of BDNF in Pax2 Lineage-Derived Interneuron Precursors in the Hindbrain Hampers the Proportion of Excitation/Inhibition, Learning, and Behavior
por: Eckert, Philipp, et al.
Publicado: (2021)

The CaMKII phosphorylation site Thr1604 in the Ca(V)1.2 channel is involved in pathological myocardial hypertrophy in rats
por: Li, Jingyuan, et al.
Publicado: (2020)

Ca(2+)-dependent Inactivation of Ca(V)1.2 Channels Prevents Gd(3+) Block: Does Ca(2+) Block the Pore of Inactivated Channels?
por: Babich, Olga, et al.
Publicado: (2007)

Aldosterone-Induced Sarco/Endoplasmic Reticulum Ca(2+) Pump Upregulation Counterbalances Ca(v)1.2-Mediated Ca(2+) Influx in Mesenteric Arteries
por: Salazar-Enciso, Rogelio, et al.
Publicado: (2022)

PIKfyve regulates Ca(V)1.2 degradation and prevents excitotoxic cell death
por: Tsuruta, Fuminori, et al.
Publicado: (2009)

α(1)-Adrenergic receptor–PKC–Pyk2–Src signaling boosts L-type Ca(2+) channel Ca(V)1.2 activity and long-term potentiation in rodents
por: Man, Kwun Nok Mimi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e3raido1eu07s6pl9sv2bt063d