Prevention and treatment of biofilms by hybrid- and nanotechnologies

Bacteria growing as adherent biofilms are difficult to treat and frequently develop resistance to antimicrobial agents. To counter biofilms, various approaches, including prevention of bacterial surface adherence, application of device applicators, and assimilation of antimicrobials in targeted drug...

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Detalles Bibliográficos
Autores principales: Kasimanickam, Ramanathan K, Ranjan, Ashish, Asokan, GV, Kasimanickam, Vanmathy R, Kastelic, John P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739460/
https://www.ncbi.nlm.nih.gov/pubmed/23946652
http://dx.doi.org/10.2147/IJN.S44100
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author Kasimanickam, Ramanathan K
Ranjan, Ashish
Asokan, GV
Kasimanickam, Vanmathy R
Kastelic, John P
author_facet Kasimanickam, Ramanathan K
Ranjan, Ashish
Asokan, GV
Kasimanickam, Vanmathy R
Kastelic, John P
author_sort Kasimanickam, Ramanathan K
collection PubMed
description Bacteria growing as adherent biofilms are difficult to treat and frequently develop resistance to antimicrobial agents. To counter biofilms, various approaches, including prevention of bacterial surface adherence, application of device applicators, and assimilation of antimicrobials in targeted drug delivery machinery, have been utilized. These methods are also combined to achieve synergistic bacterial killing. This review discusses various multimodal technologies, presents general concepts, and describes therapies relying on the principles of electrical energy, ultrasound, photodynamics, and targeted drug delivery for prevention and treatment of biofilms.
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spelling pubmed-37394602013-08-14 Prevention and treatment of biofilms by hybrid- and nanotechnologies Kasimanickam, Ramanathan K Ranjan, Ashish Asokan, GV Kasimanickam, Vanmathy R Kastelic, John P Int J Nanomedicine Review Bacteria growing as adherent biofilms are difficult to treat and frequently develop resistance to antimicrobial agents. To counter biofilms, various approaches, including prevention of bacterial surface adherence, application of device applicators, and assimilation of antimicrobials in targeted drug delivery machinery, have been utilized. These methods are also combined to achieve synergistic bacterial killing. This review discusses various multimodal technologies, presents general concepts, and describes therapies relying on the principles of electrical energy, ultrasound, photodynamics, and targeted drug delivery for prevention and treatment of biofilms. Dove Medical Press 2013 2013-08-02 /pmc/articles/PMC3739460/ /pubmed/23946652 http://dx.doi.org/10.2147/IJN.S44100 Text en © 2013 Kasimanickam et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Kasimanickam, Ramanathan K
Ranjan, Ashish
Asokan, GV
Kasimanickam, Vanmathy R
Kastelic, John P
Prevention and treatment of biofilms by hybrid- and nanotechnologies
title Prevention and treatment of biofilms by hybrid- and nanotechnologies
title_full Prevention and treatment of biofilms by hybrid- and nanotechnologies
title_fullStr Prevention and treatment of biofilms by hybrid- and nanotechnologies
title_full_unstemmed Prevention and treatment of biofilms by hybrid- and nanotechnologies
title_short Prevention and treatment of biofilms by hybrid- and nanotechnologies
title_sort prevention and treatment of biofilms by hybrid- and nanotechnologies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739460/
https://www.ncbi.nlm.nih.gov/pubmed/23946652
http://dx.doi.org/10.2147/IJN.S44100
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