Equivalent T Cell Epitope Promiscuity in Ecologically Diverse Human Pathogens

BACKGROUND: The HLA (human leukocyte antigen) molecules that present pathogen-derived epitopes to T cells are highly diverse. Correspondingly, many pathogens such as HIV evolve epitope variants in order to evade immune recognition. In contrast, another persistent human pathogen, Mycobacterium tuberc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiens, Kirsten E., Swaminathan, Harish, Copin, Richard, Lun, Desmond S., Ernst, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739752/
https://www.ncbi.nlm.nih.gov/pubmed/23951341
http://dx.doi.org/10.1371/journal.pone.0073124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739752/
https://www.ncbi.nlm.nih.gov/pubmed/23951341
http://dx.doi.org/10.1371/journal.pone.0073124

Ejemplares similares