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Equivalent T Cell Epitope Promiscuity in Ecologically Diverse Human Pathogens

BACKGROUND: The HLA (human leukocyte antigen) molecules that present pathogen-derived epitopes to T cells are highly diverse. Correspondingly, many pathogens such as HIV evolve epitope variants in order to evade immune recognition. In contrast, another persistent human pathogen, Mycobacterium tuberc...

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Detalles Bibliográficos
Autores principales:	Wiens, Kirsten E., Swaminathan, Harish, Copin, Richard, Lun, Desmond S., Ernst, Joel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739752/ https://www.ncbi.nlm.nih.gov/pubmed/23951341 http://dx.doi.org/10.1371/journal.pone.0073124

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