Improvement of a Predictive Model of Castration-Resistant Prostate Cancer: Functional Genetic Variants in TGFβ1 Signaling Pathway Modulation

Prostate cancer (PC) is the most frequently diagnosed cancer in men. The acquisition of castration-resistant (CR) phenotype is associated with the activation of signaling pathways mediated by growth factors. The TGFβ1 and its receptors have an important role in tumor progression, being the pro-apopt...

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Detalles Bibliográficos
Autores principales: Teixeira, Ana L., Gomes, Mónica, Nogueira, Augusto, Azevedo, Andreia S., Assis, Joana, Dias, Francisca, Santos, Juliana I., Lobo, Francisco, Morais, António, Maurício, Joaquina, Medeiros, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739770/
https://www.ncbi.nlm.nih.gov/pubmed/23951322
http://dx.doi.org/10.1371/journal.pone.0072419

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