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Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

OBJECTIVE: The inner mucus layer in mouse colon normally separates bacteria from the epithelium. Do humans have a similar inner mucus layer and are defects in this mucus layer a common denominator for spontaneous colitis in mice models and ulcerative colitis (UC)? METHODS AND RESULTS: The colon mucu...

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Detalles Bibliográficos
Autores principales:	Johansson, Malin E V, Gustafsson, Jenny K, Holmén-Larsson, Jessica, Jabbar, Karolina S, Xia, Lijun, Xu, Hua, Ghishan, Fayez K, Carvalho, Frederic A, Gewirtz, Andrew T, Sjövall, Henrik, Hansson, Gunnar C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2014
Materias:	Inflammatory Bowel Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740207/ https://www.ncbi.nlm.nih.gov/pubmed/23426893 http://dx.doi.org/10.1136/gutjnl-2012-303207

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