RAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancer

The transcription coactivator Yes-associated protein 1 (YAP1) is regulated by the Hippo tumor suppressor pathway. However, the role of YAP1 in thyroid cancer, which is frequently associated with the BRAF(V600E) mutation, remains unknown. This study aimed to investigate the role of YAP1 in thyroid ca...

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Detalles Bibliográficos
Autores principales: Lee, S E, Lee, J U, Lee, M H, Ryu, M J, Kim, S J, Kim, Y K, Choi, M J, Kim, K S, Kim, J M, Kim, J W, Koh, Y W, Lim, D-S, Jo, Y S, Shong, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740284/
https://www.ncbi.nlm.nih.gov/pubmed/23857250
http://dx.doi.org/10.1038/oncsis.2013.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740284/
https://www.ncbi.nlm.nih.gov/pubmed/23857250
http://dx.doi.org/10.1038/oncsis.2013.12

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