Cargando…
RAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancer
The transcription coactivator Yes-associated protein 1 (YAP1) is regulated by the Hippo tumor suppressor pathway. However, the role of YAP1 in thyroid cancer, which is frequently associated with the BRAF(V600E) mutation, remains unknown. This study aimed to investigate the role of YAP1 in thyroid ca...
Autores principales: | Lee, S E, Lee, J U, Lee, M H, Ryu, M J, Kim, S J, Kim, Y K, Choi, M J, Kim, K S, Kim, J M, Kim, J W, Koh, Y W, Lim, D-S, Jo, Y S, Shong, M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740284/ https://www.ncbi.nlm.nih.gov/pubmed/23857250 http://dx.doi.org/10.1038/oncsis.2013.12 |
Ejemplares similares
-
Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors
por: Marusiak, Anna A., et al.
Publicado: (2014) -
Arabidopsis Raf-Like Kinase Raf10 Is a Regulatory Component of Core ABA Signaling
por: Nguyen, Quy Thi Cam, et al.
Publicado: (2019) -
Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation
por: Rhee, Yong-Hee, et al.
Publicado: (2016) -
Involvement of protein kinase C, phospholipase C, and protein tyrosine kinase pathways in oxygen radical generation by asbestos-stimulated alveolar macrophage.
por: Lim, Y, et al.
Publicado: (1997) -
Calcium/calmodulin kinase II activity of hippocampus in kainate-induced epilepsy.
por: Lee, M. C., et al.
Publicado: (2001)