Cargando…
Comparison of In Vivo Effects of Insulin on SREBP-1c Activation and INSIG-1/2 in Rat Liver and Human and Rat Adipose Tissue
The stimulatory effects of insulin on de novo lipogenesis (DNL) in the liver, where it is an important contributor to non-alcoholic fatty liver disease (NAFLD), hepatic and systemic insulin resistance, is strong and well established. In contrast, insulin plays only a minor role in DNL in adipose tis...
Autores principales: | Boden, Guenther, Salehi, Sajad, Cheung, Peter, Homko, Carol, Song, Weiwei, Loveland-Jones, Catherine, Jayarajan, Senthil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740458/ https://www.ncbi.nlm.nih.gov/pubmed/23913732 http://dx.doi.org/10.1002/oby.20134 |
Ejemplares similares
-
Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue
por: Boden, Guenther, et al.
Publicado: (2014) -
Response to Comment on Boden et al. Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue. Diabetes 2014;63:912–922
por: Boden, Guenther, et al.
Publicado: (2014) -
Insulin Resistance Is Associated With Diminished Endoplasmic Reticulum Stress Responses in Adipose Tissue of Healthy and Diabetic Subjects
por: Boden, Guenther, et al.
Publicado: (2014) -
Increase in Endoplasmic Reticulum Stress–Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals
por: Boden, Guenther, et al.
Publicado: (2008) -
Overexpression of Insig-1 protects β cell against glucolipotoxicity via SREBP-1c
por: Chen, Ke, et al.
Publicado: (2011)