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Synthesis of the calcilytic ligand NPS 2143

(R)-3 (NPS 2143) is a negative allosteric modulator of the human calcium-sensing receptor (CaSR) and as such represents an important pharmacological tool compound for studying the CaSR. Herein, we disclose for the first time a complete experimental description, detailed characterisation and assessme...

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Detalles Bibliográficos
Autores principales:	Johansson, Henrik, Cailly, Thomas, Rojas Bie Thomsen, Alex, Bräuner-Osborne, Hans, Sejer Pedersen, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740522/ https://www.ncbi.nlm.nih.gov/pubmed/23946832 http://dx.doi.org/10.3762/bjoc.9.154

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