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Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production

The preparation of novel multi-substituted 1,2,3-triazole-modified β-aminocyclohexanecarboxylic acid derivatives in a simple and efficient continuous-flow procedure is reported. The 1,3-dipolar cycloaddition reactions were performed with copper powder as a readily accessible Cu(I) source. Initially,...

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Detalles Bibliográficos
Autores principales:	Ötvös, Sándor B, Georgiádes, Ádám, Mándity, István M, Kiss, Lóránd, Fülöp, Ferenc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740622/ https://www.ncbi.nlm.nih.gov/pubmed/23946850 http://dx.doi.org/10.3762/bjoc.9.172

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