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Distinct Gene Expression Signatures in Lynch Syndrome and Familial Colorectal Cancer Type X

INTRODUCTION: Heredity is estimated to cause at least 20% of colorectal cancer. The hereditary nonpolyposis colorectal cancer subset is divided into Lynch syndrome and familial colorectal cancer type X (FCCTX) based on presence of mismatch repair (MMR) gene defects. PURPOSE: We addressed the gene ex...

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Detalles Bibliográficos
Autores principales: Dominguez-Valentin, Mev, Therkildsen, Christina, Veerla, Srinivas, Jönsson, Mats, Bernstein, Inge, Borg, Åke, Nilbert, Mef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741139/
https://www.ncbi.nlm.nih.gov/pubmed/23951239
http://dx.doi.org/10.1371/journal.pone.0071755