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Link between Epigenomic Alterations and Genome-Wide Aberrant Transcriptional Response to Allergen in Dendritic Cells Conveying Maternal Asthma Risk
We investigated the link between epigenome-wide methylation aberrations at birth and genomic transcriptional changes upon allergen sensitization that occur in the neonatal dendritic cells (DC) due to maternal asthma. We previously demonstrated that neonates of asthmatic mothers are born with a funct...
Autores principales: | Mikhaylova, Lyudmila, Zhang, Yiming, Kobzik, Lester, Fedulov, Alexey V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741290/ https://www.ncbi.nlm.nih.gov/pubmed/23950928 http://dx.doi.org/10.1371/journal.pone.0070387 |
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