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Identification of Novel Gene Targets and Functions of p21-Activated Kinase 1 during DNA Damage by Gene Expression Profiling

P21-activated kinase 1 (PAK1), a serine/threonine protein kinase, modulates many cellular processes by phosphorylating its downstream substrates. In addition to its role in the cytoplasm, PAK1 also affects gene transcription due to its nuclear localization and association with chromatin. It is now r...

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Detalles Bibliográficos
Autores principales: Motwani, Mona, Li, Da-Qiang, Horvath, Anelia, Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741304/
https://www.ncbi.nlm.nih.gov/pubmed/23950862
http://dx.doi.org/10.1371/journal.pone.0066585

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