The GPVI – Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times

AIMS: Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated platelet activation has the potential to combine shor...

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Detalles Bibliográficos
Autores principales: Ungerer, Martin, Li, Zhongmin, Baumgartner, Christine, Goebel, Silvia, Vogelmann, Jasmin, Holthoff, Hans-Peter, Gawaz, Meinrad, Münch, Götz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741334/
https://www.ncbi.nlm.nih.gov/pubmed/23951109
http://dx.doi.org/10.1371/journal.pone.0071193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741334/
https://www.ncbi.nlm.nih.gov/pubmed/23951109
http://dx.doi.org/10.1371/journal.pone.0071193

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