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The GPVI – Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times
AIMS: Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated platelet activation has the potential to combine shor...
Autores principales: | Ungerer, Martin, Li, Zhongmin, Baumgartner, Christine, Goebel, Silvia, Vogelmann, Jasmin, Holthoff, Hans-Peter, Gawaz, Meinrad, Münch, Götz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741334/ https://www.ncbi.nlm.nih.gov/pubmed/23951109 http://dx.doi.org/10.1371/journal.pone.0071193 |
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