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Genetic Variation in the Base Excision Repair Pathway, Environmental Risk Factors, and Colorectal Adenoma Risk

Cigarette smoking, high alcohol intake, and low dietary folate levels are risk factors for colorectal adenomas. Oxidative damage caused by these three factors can be repaired through the base excision repair pathway (BER). We hypothesized that genetic variation in BER might modify colorectal adenoma...

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Detalles Bibliográficos
Autores principales:	Corral, Roman, Lewinger, Juan Pablo, Joshi, Amit D., Levine, A. Joan, Vandenberg, David J., Haile, Robert W., Stern, Mariana C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741365/ https://www.ncbi.nlm.nih.gov/pubmed/23951112 http://dx.doi.org/10.1371/journal.pone.0071211

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