IL-1α Expression in Pancreatic Ductal Adenocarcinoma Affects the Tumor Cell Migration and Is Regulated by the p38MAPK Signaling Pathway

The interplay between the tumor cells and the surrounding stroma creates inflammation, which promotes tumor growth and spread. The inflammation is a hallmark for pancreatic adenocarcinoma (PDAC) and is to high extent driven by IL-1α. IL-1α is expressed and secreted by the tumor cells and exerting it...

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Detalles Bibliográficos
Autores principales: Tjomsland, Vegard, Bojmar, Linda, Sandström, Per, Bratthäll, Charlotte, Messmer, Davorka, Spångeus, Anna, Larsson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741369/
https://www.ncbi.nlm.nih.gov/pubmed/23951028
http://dx.doi.org/10.1371/journal.pone.0070874

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