Radicicol Inhibits iNOS Expression in Cytokine-Stimulated Pancreatic Beta Cells

Here, we show that radicicol, a fungal antibiotic, resulted in marked inhibition of inducible nitric oxide synthase (iNOS) transcription by the pancreatic beta cell line MIN6N8a in response to cytokine mixture (CM: TNF-α, IFN-γ, and IL-1β). Treatment of MIN6N8a cells with radicicol inhibited CM-stim...

Descripción completa

Detalles Bibliográficos
Autores principales: Youn, Cha Kyung, Park, Seon Joo, Li, Mei Hong, Lee, Min Young, Lee, Kun Yeong, Cha, Man Jin, Kim, Ok Hyeun, You, Ho Jin, Chang, In Youp, Yoon, Sang Pil, Jeon, Young Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741488/
https://www.ncbi.nlm.nih.gov/pubmed/23946691
http://dx.doi.org/10.4196/kjpp.2013.17.4.315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741488/
https://www.ncbi.nlm.nih.gov/pubmed/23946691
http://dx.doi.org/10.4196/kjpp.2013.17.4.315

Ejemplares similares