In Vitro Antifungal Activity of Equol against Candida albicans

In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 µM, respectively. Two separate viability assays found that equol changed the integrity of the C. a...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Ah, Chee, Hee Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Mycology 2010
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741528/
https://www.ncbi.nlm.nih.gov/pubmed/23956675
http://dx.doi.org/10.4489/MYCO.2010.38.4.328
Descripción
Sumario:In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 µM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.

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