In Vitro Antifungal Activity of Equol against Candida albicans

In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 µM, respectively. Two separate viability assays found that equol changed the integrity of the C. a...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Ah, Chee, Hee Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Mycology 2010
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741528/
https://www.ncbi.nlm.nih.gov/pubmed/23956675
http://dx.doi.org/10.4489/MYCO.2010.38.4.328
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author Lee, Jeong Ah
Chee, Hee Youn
author_facet Lee, Jeong Ah
Chee, Hee Youn
author_sort Lee, Jeong Ah
collection PubMed
description In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 µM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.
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spelling pubmed-37415282013-08-16 In Vitro Antifungal Activity of Equol against Candida albicans Lee, Jeong Ah Chee, Hee Youn Mycobiology Research Note In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 µM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes. The Korean Society of Mycology 2010-12 2010-12-31 /pmc/articles/PMC3741528/ /pubmed/23956675 http://dx.doi.org/10.4489/MYCO.2010.38.4.328 Text en © The Korean Society of Mycology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Note
Lee, Jeong Ah
Chee, Hee Youn
In Vitro Antifungal Activity of Equol against Candida albicans
title In Vitro Antifungal Activity of Equol against Candida albicans
title_full In Vitro Antifungal Activity of Equol against Candida albicans
title_fullStr In Vitro Antifungal Activity of Equol against Candida albicans
title_full_unstemmed In Vitro Antifungal Activity of Equol against Candida albicans
title_short In Vitro Antifungal Activity of Equol against Candida albicans
title_sort in vitro antifungal activity of equol against candida albicans
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741528/
https://www.ncbi.nlm.nih.gov/pubmed/23956675
http://dx.doi.org/10.4489/MYCO.2010.38.4.328
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