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Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran

BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old chil...

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Detalles Bibliográficos
Autores principales: Taghavi Ardakani, Abbas, Soltani, Babak, Sehat, Mojtaba, Namjoo, Somayeh, Haji Rezaei, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741904/
https://www.ncbi.nlm.nih.gov/pubmed/23967019
http://dx.doi.org/10.5812/hepatmon.10553
Descripción
Sumario:BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. PATIENTS AND METHODS: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). RESULTS: Totally, 3.9% of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. CONCLUSIONS: In this city, a great proportion of children are susceptible to hepatitis A and it’s complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found.