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Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran

BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old chil...

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Autores principales: Taghavi Ardakani, Abbas, Soltani, Babak, Sehat, Mojtaba, Namjoo, Somayeh, Haji Rezaei, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741904/
https://www.ncbi.nlm.nih.gov/pubmed/23967019
http://dx.doi.org/10.5812/hepatmon.10553
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author Taghavi Ardakani, Abbas
Soltani, Babak
Sehat, Mojtaba
Namjoo, Somayeh
Haji Rezaei, Mostafa
author_facet Taghavi Ardakani, Abbas
Soltani, Babak
Sehat, Mojtaba
Namjoo, Somayeh
Haji Rezaei, Mostafa
author_sort Taghavi Ardakani, Abbas
collection PubMed
description BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. PATIENTS AND METHODS: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). RESULTS: Totally, 3.9% of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. CONCLUSIONS: In this city, a great proportion of children are susceptible to hepatitis A and it’s complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found.
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spelling pubmed-37419042013-08-21 Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran Taghavi Ardakani, Abbas Soltani, Babak Sehat, Mojtaba Namjoo, Somayeh Haji Rezaei, Mostafa Hepat Mon Research Article BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. PATIENTS AND METHODS: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). RESULTS: Totally, 3.9% of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. CONCLUSIONS: In this city, a great proportion of children are susceptible to hepatitis A and it’s complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found. Kowsar 2013-05-27 /pmc/articles/PMC3741904/ /pubmed/23967019 http://dx.doi.org/10.5812/hepatmon.10553 Text en Copyright © 2013, Kowsar Corp.; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Taghavi Ardakani, Abbas
Soltani, Babak
Sehat, Mojtaba
Namjoo, Somayeh
Haji Rezaei, Mostafa
Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title_full Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title_fullStr Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title_full_unstemmed Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title_short Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
title_sort seroprevalence of anti-hepatitis a antibody among 1 - 15 year old children in kashan-iran
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741904/
https://www.ncbi.nlm.nih.gov/pubmed/23967019
http://dx.doi.org/10.5812/hepatmon.10553
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