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Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran
BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old chil...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741904/ https://www.ncbi.nlm.nih.gov/pubmed/23967019 http://dx.doi.org/10.5812/hepatmon.10553 |
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author | Taghavi Ardakani, Abbas Soltani, Babak Sehat, Mojtaba Namjoo, Somayeh Haji Rezaei, Mostafa |
author_facet | Taghavi Ardakani, Abbas Soltani, Babak Sehat, Mojtaba Namjoo, Somayeh Haji Rezaei, Mostafa |
author_sort | Taghavi Ardakani, Abbas |
collection | PubMed |
description | BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. PATIENTS AND METHODS: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). RESULTS: Totally, 3.9% of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. CONCLUSIONS: In this city, a great proportion of children are susceptible to hepatitis A and it’s complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found. |
format | Online Article Text |
id | pubmed-3741904 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-37419042013-08-21 Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran Taghavi Ardakani, Abbas Soltani, Babak Sehat, Mojtaba Namjoo, Somayeh Haji Rezaei, Mostafa Hepat Mon Research Article BACKGROUND: Worldwide, hepatitis A is a common infection during childhood especially in developing countries. It can cause severe complications in adults and patients with underlying diseases. OBJECTIVES: This study was performed to determine the seroprevalence of hepatitis A in 1 - 15 year-old children of Kashan. PATIENTS AND METHODS: This cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in Kashan city during 2012. Total antibodies against hepatitis A were measured in sera by enzyme-linked immunosorbent assay (ELISA). RESULTS: Totally, 3.9% of children were seropositive. Mean number of family members was 3.92 ± 0.89. There was no difference in seroprevalence of hepatitis A relative to sex, family size, mean age and age groups. CONCLUSIONS: In this city, a great proportion of children are susceptible to hepatitis A and it’s complications at an older age. This decrease in seropositivity may be caused by elevated hygien level. According to our results hepatitis A vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis A infection is found. Kowsar 2013-05-27 /pmc/articles/PMC3741904/ /pubmed/23967019 http://dx.doi.org/10.5812/hepatmon.10553 Text en Copyright © 2013, Kowsar Corp.; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Taghavi Ardakani, Abbas Soltani, Babak Sehat, Mojtaba Namjoo, Somayeh Haji Rezaei, Mostafa Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title | Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title_full | Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title_fullStr | Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title_full_unstemmed | Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title_short | Seroprevalence of Anti-Hepatitis A Antibody Among 1 - 15 Year Old Children in Kashan-Iran |
title_sort | seroprevalence of anti-hepatitis a antibody among 1 - 15 year old children in kashan-iran |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741904/ https://www.ncbi.nlm.nih.gov/pubmed/23967019 http://dx.doi.org/10.5812/hepatmon.10553 |
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