JNK1/2 Activation by an Extract from the Roots of Morus alba L. Reduces the Viability of Multidrug-Resistant MCF-7/Dox Cells by Inhibiting YB-1-Dependent MDR1 Expression

Cancer cells acquire anticancer drug resistance during chemotherapy, which aggravates cancer disease. MDR1 encoded from multidrug resistance gene 1 mainly causes multidrug resistance phenotypes of different cancer cells. In this study, we demonstrate that JNK1/2 activation by an extract from the roo...

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Detalles Bibliográficos
Autores principales: Choi, Youn Kyung, Cho, Sung-Gook, Choi, Hyeong Sim, Woo, Sang-Mi, Yun, Yee Jin, Shin, Yong Cheol, Ko, Seong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741934/
https://www.ncbi.nlm.nih.gov/pubmed/23983799
http://dx.doi.org/10.1155/2013/741985

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