Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different...

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Autores principales: Mennan, Claire, Wright, Karina, Bhattacharjee, Atanu, Balain, Birender, Richardson, James, Roberts, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741948/
https://www.ncbi.nlm.nih.gov/pubmed/23984420
http://dx.doi.org/10.1155/2013/916136
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author Mennan, Claire
Wright, Karina
Bhattacharjee, Atanu
Balain, Birender
Richardson, James
Roberts, Sally
author_facet Mennan, Claire
Wright, Karina
Bhattacharjee, Atanu
Balain, Birender
Richardson, James
Roberts, Sally
author_sort Mennan, Claire
collection PubMed
description Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.
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spelling pubmed-37419482013-08-27 Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord Mennan, Claire Wright, Karina Bhattacharjee, Atanu Balain, Birender Richardson, James Roberts, Sally Biomed Res Int Research Article Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics. Hindawi Publishing Corporation 2013 2013-07-25 /pmc/articles/PMC3741948/ /pubmed/23984420 http://dx.doi.org/10.1155/2013/916136 Text en Copyright © 2013 Claire Mennan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mennan, Claire
Wright, Karina
Bhattacharjee, Atanu
Balain, Birender
Richardson, James
Roberts, Sally
Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_full Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_fullStr Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_full_unstemmed Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_short Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_sort isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741948/
https://www.ncbi.nlm.nih.gov/pubmed/23984420
http://dx.doi.org/10.1155/2013/916136
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