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β-Cyclodextrin Inclusion Complex to Improve Physicochemical Properties of Pipemidic Acid: Characterization and Bioactivity Evaluation

The aptitude of cyclodextrins (CDs) to form host-guest complexes has prompted an increase in the development of new drug formulations. In this study, the inclusion complexes of pipemidic acid (HPPA), a therapeutic agent for urinary tract infections, with native β-CD were prepared in solid state by k...

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Detalles Bibliográficos
Autores principales: Iacovino, Rosa, Rapuano, Filomena, Caso, Jolanda Valentina, Russo, Agostino, Lavorgna, Margherita, Russo, Chiara, Isidori, Marina, Russo, Luigi, Malgieri, Gaetano, Isernia, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742172/
https://www.ncbi.nlm.nih.gov/pubmed/23799358
http://dx.doi.org/10.3390/ijms140713022