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Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR

We propose a kinetic model for the activation of the las regulon in the opportunistic pathogen Pseudomonas aeruginosa. The model is based on in vitro data and accounts for the LasR dimerization and consecutive activation by binding of two OdDHL signal molecules. Experimentally, the production of the...

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Detalles Bibliográficos
Autores principales:	Claussen, Anetta, Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, Martin, Ferkinghoff-Borg, Jesper, Sams, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742191/ https://www.ncbi.nlm.nih.gov/pubmed/23807499 http://dx.doi.org/10.3390/ijms140713360

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