Gene Expression Analyses Support Fallopian Tube Epithelium as the Cell of Origin of Epithelial Ovarian Cancer

Folate receptor alpha (FOLR1/FRA) is reported to be overexpressed in epithelial ovarian cancers (EOC), especially the serous histotype. Further, while dysregulation of the folate-dependent 1-carbon cycle has been implicated in tumorogenesis, little is known relative to the potential mechanism of act...

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Detalles Bibliográficos
Autores principales: O’Shannessy, Daniel J., Jackson, Stephen M., Twine, Natalie C., Hoffman, Bryan E., Dezso, Zoltan, Agoulnik, Sergei I., Somers, Elizabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742211/
https://www.ncbi.nlm.nih.gov/pubmed/23880844
http://dx.doi.org/10.3390/ijms140713687

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