Cargando…

KRAS and MAPK1 Gene Amplification in Type II Ovarian Carcinomas

In this study, we examined the clinical significance of KRAS and MAPK1 amplification and assessed whether these amplified genes were potential therapeutic targets in type II ovarian carcinoma. Using fluorescence in situ hybridization, immunohistochemistry, and retrospectively collected clinical data...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rahman, Mohammed Tanjimur, Nakayama, Kentaro, Rahman, Munmun, Katagiri, Hiroshi, Katagiri, Atsuko, Ishibashi, Tomoka, Ishikawa, Masako, Sato, Emi, Iida, Kouji, Nakayama, Naomi, Ishikawa, Noriyuki, Miyazaki, Kohji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742215/ https://www.ncbi.nlm.nih.gov/pubmed/23820584 http://dx.doi.org/10.3390/ijms140713748

Ejemplares similares

CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas
por: NAKAYAMA, KENTARO, et al.
Publicado: (2015)

A Case of Stage III c Ovarian Clear Cell Carcinoma: The Role for Predictive Biomarkers and Targeted Therapies
por: Rahman, Munmun, et al.
Publicado: (2013)

Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer
por: Nakayama, Kentaro, et al.
Publicado: (2017)

Letrozole as second-line hormonal treatment for recurrent low-grade endometrial stromal sarcoma: A case report and review of the literature
por: Nakamura, Kohei, et al.
Publicado: (2016)

KRAS/BRAF Analysis in Ovarian Low-Grade Serous Carcinoma Having Synchronous All Pathological Precursor Regions
por: Nakamura, Kohei, et al.
Publicado: (2016)

Microwave endometrial ablation as an alternative to hysterectomy for the emergent control of uterine bleeding in patients who are poor surgical candidates
por: Yeasmin, Shamima, et al.
Publicado: (2008)

Loss of autophagy-related protein Beclin 1 may define poor prognosis in ovarian clear cell carcinomas
por: KATAGIRI, HIROSHI, et al.
Publicado: (2015)

Efficacy of microwave ablation for the treatment of endometrial carcinoma: A report of 3 cases
por: NAKAMURA, KOHEI, et al.
Publicado: (2016)

Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas
por: Rahman, M T, et al.
Publicado: (2012)

The diagnostic utility of PAX8 immunostaining of malignant peritoneal mesothelioma presenting as serous ovarian carcinoma: A single-center report of two cases
por: Nakamura, Kohei, et al.
Publicado: (2017)

EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target
por: Iida, K, et al.
Publicado: (2011)

Establishment of a Novel In Vitro Model of Endometriosis with Oncogenic KRAS and PIK3CA Mutations for Understanding the Underlying Biology and Molecular Pathogenesis
por: Hossain, Mohammad Mahmud, et al.
Publicado: (2021)

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma
por: Sato, Emi, et al.
Publicado: (2018)

Endometrial Serous Carcinoma: Its Molecular Characteristics and Histology-Specific Treatment Strategies
por: Nakayama, Kentaro, et al.
Publicado: (2012)

Mechanisms of Ovarian Cancer Metastasis: Biochemical Pathways
por: Nakayama, Kentaro, et al.
Publicado: (2012)

KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer
por: Nakayama, N, et al.
Publicado: (2008)

A case with life-threatening uterine bleeding due to postmenopausal uterine arteriovenous malformation
por: Sato, Emi, et al.
Publicado: (2015)

High PD-1 expression level is associated with an unfavorable prognosis in patients with cervical adenocarcinoma
por: Ishikawa, Masako, et al.
Publicado: (2020)

Genetic analysis and phosphoinositide 3-kinase/protein kinase B signaling pathway status in ovarian endometrioid borderline tumor samples
por: Nakamura, Kohei, et al.
Publicado: (2018)

Mucinous borderline ovarian tumors with BRAF(V600E) mutation may have low risk for progression to invasive carcinomas
por: Ohnishi, Kaori, et al.
Publicado: (2020)

Affinity-purified DNA-based mutation profiles of endometriosis-related ovarian neoplasms in Japanese patients
por: Ishikawa, Masako, et al.
Publicado: (2018)

P16(INK4A) expression might be associated with a favorable prognosis for cervical adenocarcinoma via dysregulation of the RB pathway
por: Ishikawa, Masako, et al.
Publicado: (2021)

Long-term outcomes of microwave endometrial ablation for treatment of patients with menorrhagia: A retrospective cohort study
por: Nakamura, Kohei, et al.
Publicado: (2017)

Identifying the Carcinogenic Mechanism of Malignant Struma Ovarii Using Whole-Exome Sequencing and DNA Methylation Analysis
por: Yamashita, Hitomi, et al.
Publicado: (2023)

Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer
por: Yamashita, Hitomi, et al.
Publicado: (2017)

Prognostic Value of Peripheral Blood Lymphocyte Telomere Length in Gynecologic Malignant Tumors
por: Shanta, Kamrunnahar, et al.
Publicado: (2020)

Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance
por: Kyo, Satoru, et al.
Publicado: (2022)

Histological and Genetic Diversity in Ovarian Mucinous Carcinomas: A Pilot Study
por: Razia, Sultana, et al.
Publicado: (2023)

Frequent PIK3CA mutation in normal endometrial gland drives spheroid formation and may be involved in stem cell propagation
por: Sato, Seiya, et al.
Publicado: (2023)

Pathological findings in the endometrium after microwave endometrial ablation
por: Nakayama, Kentaro, et al.
Publicado: (2020)

Relationship between Microsatellite Instability, Immune Cells Infiltration, and Expression of Immune Checkpoint Molecules in Ovarian Carcinoma: Immunotherapeutic Strategies for the Future
por: Yamashita, Hitomi, et al.
Publicado: (2019)

High Frequency of PIK3CA Mutations in Low-Grade Serous Ovarian Carcinomas of Japanese Patients
por: Ishibashi, Tomoka, et al.
Publicado: (2019)

Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients
por: Sasamori, Hiroki, et al.
Publicado: (2022)

The Case of an Endometrial Cancer Patient with Breast Cancer Who Has Achieved Long-Term Survival via Letrozole Monotherapy
por: Ishikawa, Masako, et al.
Publicado: (2023)

Ovarian Endometrioid and Clear Cell Carcinomas with Low Prevalence of Microsatellite Instability: A Unique Subset of Ovarian Carcinomas Could Benefit from Combination Therapy with Immune Checkpoint Inhibitors and Other Anticancer Agents
por: Nonomura, Yuki, et al.
Publicado: (2022)

Promising Therapeutic Impact of Immune Checkpoint Inhibitors in Type II Endometrial Cancer Patients with Deficient Mismatch Repair Status
por: Sawada, Kiyoka, et al.
Publicado: (2023)

Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report
por: Ishikawa, Masako, et al.
Publicado: (2021)

Whole-Exome Sequencing of Rare Site Endometriosis-Associated Cancer
por: Kurose, Sonomi, et al.
Publicado: (2021)

Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates
por: Minamoto, Toshiko, et al.
Publicado: (2020)

Comparison between bidirectional Stratafix(®) barbed suture and conventional suture in laparoscopic myomectomy: a retrospective study
por: Nakayama, Kentaro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hcbqvf8rilhmaipdk10vbar6j3