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MicroRNA-27a Is Induced by Leucine and Contributes to Leucine-Induced Proliferation Promotion in C2C12 Cells

Leucine, a branched chain amino acid, is well known to stimulate protein synthesis in skeletal muscle. However, the role of leucine in myoblast proliferation remains unclear. In this study, we found that leucine could promote proliferation of C2C12 cells. Moreover, expressions of miR-27a and myostat...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoling, Huang, Zhiqing, Chen, Daiwen, Yang, Ting, Liu, Guangmang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742232/
https://www.ncbi.nlm.nih.gov/pubmed/23880856
http://dx.doi.org/10.3390/ijms140714076