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Resveratrol Inhibits Ionising Irradiation-Induced Inflammation in MSCs by Activating SIRT1 and Limiting NLRP-3 Inflammasome Activation

IL-1β, a pro-inflammatory cytokine, has been shown to contribute to radiation injury. Sirt1, an NAD(+)-dependent class III protein deacetylase, plays an important role in the regulation of the proinflammatory cytokines involved in inflammation-associated diseases. The relationship between Sirt1 and...

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Detalles Bibliográficos
Autores principales: Fu, Yue, Wang, Yan, Du, Liqing, Xu, Chang, Cao, Jia, Fan, Tiqiang, Liu, Jianxiang, Su, Xu, Fan, Saijun, Liu, Qiang, Fan, Feiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742234/
https://www.ncbi.nlm.nih.gov/pubmed/23880858
http://dx.doi.org/10.3390/ijms140714105