Cargando…

Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model

There is a paucity of large animal models to study both the extent and the health risk of ionizing radiation exposure in humans. One promising candidate for such a model is the minipig. Here, we evaluate the minipig for its potential in γ-H2AX-based biodosimetry after exposure to ionizing radiation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moroni, Maria, Maeda, Daisuke, Whitnall, Mark H., Bonner, William M., Redon, Christophe E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742235/ https://www.ncbi.nlm.nih.gov/pubmed/23880859 http://dx.doi.org/10.3390/ijms140714119

Ejemplares similares

The Use of Gamma-H2AX as a Biodosimeter for Total-Body Radiation Exposure in Non-Human Primates
por: Redon, Christophe E., et al.
Publicado: (2010)

Study on γH2AX Expression of Lymphocytes as a Biomarker In Radiation Biodosimetry
por: Pan, Yan, et al.
Publicado: (2016)

Lymphocyte chromosomal aberration assay in radiation biodosimetry
por: Agrawala, Paban K., et al.
Publicado: (2010)

Gamma-H2AX biodosimetry for use in large scale radiation incidents: comparison of a rapid ‘96 well lyse/fix’ protocol with a routine method
por: Moquet, Jayne, et al.
Publicado: (2014)

The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition
por: Weyemi, Urbain, et al.
Publicado: (2016)

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker
por: Redon, Christophe E., et al.
Publicado: (2011)

High throughput evaluation of gamma-H2AX
por: Avondoglio, Dane, et al.
Publicado: (2009)

Development of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage
por: Wang, Qi, et al.
Publicado: (2020)

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay
por: Ji, Jiuping, et al.
Publicado: (2017)

Metabolomics in Radiation Biodosimetry: Current Approaches and Advances
por: Satyamitra, Merriline M., et al.
Publicado: (2020)

Effect of prolonging radiation delivery time on retention of gammaH2AX
por: Moiseenko, Vitali, et al.
Publicado: (2008)

Establishment of in vitro Calibration Curve for (60)Co-γ-rays Induced Phospho-53BP1 Foci, Rapid Biodosimetry and Initial Triage, and Comparative Evaluations With γH2AX and Cytogenetic Assays
por: Chaurasia, Rajesh Kumar, et al.
Publicado: (2022)

Serum microRNAs – potent biomarkers for radiation biodosimetry
por: Tomasik, Bartłomiej, et al.
Publicado: (2018)

Cytogenetically-based biodosimetry after high doses of radiation
por: Pujol-Canadell, Monica, et al.
Publicado: (2020)

Gamma-H2AX-Based Dose Estimation for Whole and Partial Body Radiation Exposure
por: Horn, Simon, et al.
Publicado: (2011)

Identification of Sensitive Serum microRNA Biomarkers for Radiation Biodosimetry
por: Jacob, Naduparambil Korah, et al.
Publicado: (2013)

A new inverse regression model applied to radiation biodosimetry
por: Higueras, Manuel, et al.
Publicado: (2015)

Radiation dose-rate effects on gene expression for human biodosimetry
por: Ghandhi, Shanaz A., et al.
Publicado: (2015)

Evaluation of the annual Canadian biodosimetry network intercomparisons
por: Wilkins, Ruth C., et al.
Publicado: (2015)

Prediction of late adverse events in pelvic cancer patients receiving definitive radiotherapy using radiation-induced gamma-H2AX foci assay
por: Someya, Masanori, et al.
Publicado: (2023)

Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry
por: Macaeva, Ellina, et al.
Publicado: (2016)

Biodosimetry of Persons Chronically Exposed to Low and Therapeutic Doses of Ionizing Radiation
por: Zedginidze, Alla, et al.
Publicado: (2016)

Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model
por: Lee, Younghyun, et al.
Publicado: (2018)

An optimized method for detecting gamma-H2AX in blood cells reveals a significant interindividual variation in the gamma-H2AX response among humans
por: Ismail, Ismail Hassan, et al.
Publicado: (2007)

Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetry
por: Noda, Asao
Publicado: (2018)

A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays
por: Shuryak, Igor, et al.
Publicado: (2022)

Linking Gamma-H2AX Foci and Cancer in Rat Skin Exposed to Heavy Ions and Electron Radiation
por: Burns, Fredric J., et al.
Publicado: (2015)

Simultaneous effect of gamma and Wi-Fi radiation on gamma-H2Ax expression in peripheral blood of rat: A radio-protection note
por: Khodamoradi, Ehsan, et al.
Publicado: (2022)

Collective radiation biodosimetry for dose reconstruction of acute accidental exposures: a review.
por: Pass, B
Publicado: (1997)

Strong Correlation among Three Biodosimetry Techniques Following Exposures to Ionizing Radiation
por: Kang, Chang-Mo, et al.
Publicado: (2016)

Analytical and quasi-Bayesian methods as development of the iterative approach for mixed radiation biodosimetry
por: Słonecka, Iwona, et al.
Publicado: (2018)

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
por: Shirley, Ben, et al.
Publicado: (2017)

Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease
por: Mukherjee, Sanjay, et al.
Publicado: (2019)

Optimized automated data analysis for the cytokinesis‐block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry
por: Rodrigues, M. A., et al.
Publicado: (2016)

Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures
por: Mariotti, Luca G., et al.
Publicado: (2013)

A statistical framework for radiation dose estimation with uncertainty quantification from the γ-H2AX assay
por: Einbeck, Jochen, et al.
Publicado: (2018)

Identifying radiation responsive exon-regions of genes often used for biodosimetry and acute radiation syndrome prediction
por: Schüle, Simone, et al.
Publicado: (2022)

Toward the development of transcriptional biodosimetry for the identification of irradiated individuals and assessment of absorbed radiation dose
por: Brzóska, Kamil, et al.
Publicado: (2015)

Biodosimetry of Low Dose Ionizing Radiation Using DNA Repair Foci in Human Lymphocytes
por: Jakl, Lukáš, et al.
Publicado: (2020)

Chromosome translocations: a biomarker for retrospective biodosimetry.
por: Lucas, J N
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_45d2gok01sg11ppcc2kun94d9s