Cargando…

Accelerated Evolution of the ASPM Gene Controlling Brain Size Begins Prior to Human Brain Expansion

Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by global reduction in cerebral cortical volume. The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may have been evolutionary targets in the expansion of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kouprina, Natalay, Pavlicek, Adam, Mochida, Ganeshwaran H, Solomon, Gregory, Gersch, William, Yoon, Young-Ho, Collura, Randall, Ruvolo, Maryellen, Barrett, J. Carl, Woods, C. Geoffrey, Walsh, Christopher A, Jurka, Jerzy, Larionov, Vladimir
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC374243/ https://www.ncbi.nlm.nih.gov/pubmed/15045028 http://dx.doi.org/10.1371/journal.pbio.0020126

Ejemplares similares

Recent advances in chromosome engineering
por: Kouprina, Natalay, et al.
Publicado: (2015)

TAR Cloning: Perspectives for Functional Genomics, Biomedicine, and Biotechnology
por: Kouprina, Natalay, et al.
Publicado: (2019)

Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC)
por: Kouprina, Natalay, et al.
Publicado: (2018)

Highly Selective, CRISPR/Cas9‐Mediated Isolation of Genes and Genomic Loci from Complex Genomes by TAR Cloning in Yeast
por: Kouprina, Natalay, et al.
Publicado: (2021)

Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast
por: Lee, Nicholas C.O., et al.
Publicado: (2015)

Moving toward a higher efficiency of microcell-mediated chromosome transfer
por: Liskovykh, Mikhail, et al.
Publicado: (2016)

Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineage
por: Pavlicek, Adam, et al.
Publicado: (2006)

Evolutionary Diversification of SPANX-N Sperm Protein Gene Structure and Expression
por: Kouprina, Natalay, et al.
Publicado: (2007)

A general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeast
por: Noskov, Vladimir N, et al.
Publicado: (2003)

Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes
por: Noskov, Vladimir N, et al.
Publicado: (2011)

Assembly of Multiple Full‐Size Genes or Genomic DNA Fragments on Human Artificial Chromosomes Using the Iterative Integration System
por: Lee, Nicholas C. O., et al.
Publicado: (2021)

The Multiple Mitotic Roles of the ASPM Orthologous Proteins: Insight into the Etiology of ASPM-Dependent Microcephaly
por: Razuvaeva, Alyona V., et al.
Publicado: (2023)

The molecular landscape of ASPM mutations in primary microcephaly
por: Nicholas, A K, et al.
Publicado: (2009)

Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function
por: Kononenko, Artem V., et al.
Publicado: (2013)

Zika Virus: Learning from the Past as We Prepare for the Future
por: Mochida, Ganeshwaran H.
Publicado: (2020)

Human ASPM participates in spindle organisation, spindle orientation and cytokinesis
por: Higgins, Julie, et al.
Publicado: (2010)

Rapid generation of long synthetic tandem repeats and its application for analysis in human artificial chromosome formation
por: Ebersole, Tom, et al.
Publicado: (2005)

No evidence that polymorphisms of brain regulator genes Microcephalin and ASPM are associated with general mental ability, head circumference or altruism
por: Rushton, J. Philippe, et al.
Publicado: (2007)

Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTA(VP64) expression cassette
por: Kononenko, Artem V., et al.
Publicado: (2015)

Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies
por: Pesenti, Elisa, et al.
Publicado: (2018)

The Derived Allele of ASPM Is Associated with Lexical Tone Perception
por: Wong, Patrick C. M., et al.
Publicado: (2012)

Smoothness priors analysis of time series
por: Kitagawa, Genshiro, et al.
Publicado: (1996)

Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies
por: Kouprina, Natalay, et al.
Publicado: (2018)

Primary microcephaly caused by novel compound heterozygous mutations in ASPM
por: Okamoto, Nobuhiko, et al.
Publicado: (2018)

ASPM and TROAP gene expression as potential malignant tumor markers
por: Liu, Han, et al.
Publicado: (2022)

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function
por: Kononenko, Artem V., et al.
Publicado: (2014)

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance
por: Molina, Oscar, et al.
Publicado: (2016)

Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System
por: Lee, Nicholas C. O., et al.
Publicado: (2017)

Actively transcribed rDNA and distal junction (DJ) sequence are involved in association of NORs with nucleoli
por: Liskovykh, Mikhail, et al.
Publicado: (2023)

Breaking the HAC Barrier: Histone H3K9 acetyl/methyl balance regulates CENP-A assembly
por: Ohzeki, Jun-ichirou, et al.
Publicado: (2012)

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin
por: Booth, Daniel G., et al.
Publicado: (2016)

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells
por: Petrov, Nikolai, et al.
Publicado: (2021)

Deregulation of Microcephalin and ASPM Expression Are Correlated with Epithelial Ovarian Cancer Progression
por: Alsiary, Rawiah, et al.
Publicado: (2014)

Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
por: Jiang, Kai, et al.
Publicado: (2017)

Normal early development in siblings with novel compound heterozygous variants in ASPM
por: Moriwaki, Taro, et al.
Publicado: (2020)

Oncogenic ASPM Is a Regulatory Hub of Developmental and Stemness Signaling in Cancers
por: Tsai, Kelvin K., et al.
Publicado: (2023)

The neurological and non-neurological roles of the primary microcephaly-associated protein ASPM
por: Wu, Xingxuan, et al.
Publicado: (2023)

Congenital brain abnormalities during a Zika virus epidemic in Salvador, Brazil, April 2015 to July 2016
por: Kikuti, Mariana, et al.
Publicado: (2018)

Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells
por: Kim, Jung-Hyun, et al.
Publicado: (2016)

Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient
por: Kouprina, Natalay, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_g6urvs4s848n3olst9uskniim4