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Development of an Efficient Targeted Cell-SELEX Procedure for DNA Aptamer Reagents
BACKGROUND: DNA aptamers generated by cell-SELEX offer an attractive alternative to antibodies, but generating aptamers to specific, known membrane protein targets has proven challenging, and has severely limited the use of aptamers as affinity reagents for cell identification and purification. METH...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742456/ https://www.ncbi.nlm.nih.gov/pubmed/23967247 http://dx.doi.org/10.1371/journal.pone.0071798 |